Scientist II, mRNA Research & Production

About the role

Profluent is an AI-first protein design company. Founded in 2022, we develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. Based in Emeryville, CA, we are backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date.

Profluent is seeking a highly motivated Scientist II to drive mRNA production and process development for our customized base editor programs. This is a hands-on, lab-based role focused on the synthesis, purification, characterization, and optimization of research-grade mRNA for high-throughput screening, cell-based assays, and scaled production for mouse studies.

This individual will serve as the technical lead for Profluent’s internal mRNA production core function, bridging molecular design and high-quality material generation for in vitro and in vivo studies. The successful candidate will bring strong experience with IVT-based mRNA production, template preparation, purifi

Skills